diff --git a/src/main/cli.ts b/src/main/cli.ts
index 83f77cb..fc0db35 100644
--- a/src/main/cli.ts
+++ b/src/main/cli.ts
@@ -6,6 +6,7 @@
 
 import { app } from "electron";
 import { basename } from "path";
+import { ShortcutAction } from "renderer/globalShortcuts/ShortcutSettings";
 import { stripIndent } from "shared/utils/text";
 import { parseArgs, ParseArgsOptionDescriptor } from "util";
 
@@ -42,6 +43,19 @@ const options = {
         type: "string",
         description: "Set User-Agent to a specific operating system. May trigger anti-spam or break voice chat",
         options: ["windows", "linux", "darwin"]
+    },
+    "run-shortcut": {
+        type: "string",
+        description:
+            "Run a predefined shortcut action (for custom key binds). Vesktop has to be open for this to have any effect",
+        options: [
+            "toggleMute",
+            "toggleDeafen",
+            "toggleStreamerMode",
+            "toggleCamera",
+            "toggleScreenShare",
+            "disconnectFromVoiceChannel"
+        ] satisfies Array<ShortcutAction>
     }
 } satisfies Record<string, Option>;
 
@@ -135,7 +149,7 @@ export function checkCommandLineForHelpOrVersion() {
             app.exit(1);
         }
 
-        if ("options" in def && !def.options?.includes(value as string)) {
+        if ("options" in def && !def.options?.includes(value as any)) {
             console.error(`Invalid value for --${name}: ${value}\nExpected one of: ${def.options.join(", ")}`);
             app.exit(1);
         }
diff --git a/src/main/index.ts b/src/main/index.ts
index 28a08e8..cae0fcc 100644
--- a/src/main/index.ts
+++ b/src/main/index.ts
@@ -11,9 +11,13 @@ import "./userAssets";
 import "./vesktopProtocol";
 
 import { app, BrowserWindow, nativeTheme } from "electron";
+import { IpcCommands } from "shared/IpcEvents";
 
+// eslint-disable-next-line no-duplicate-imports
+import { CommandLine } from "./cli";
 import { DATA_DIR } from "./constants";
 import { createFirstLaunchTour } from "./firstLaunch";
+import { sendRendererCommand } from "./ipcCommands";
 import { registerKeyBinds } from "./keyBinds";
 import { createWindows, mainWin } from "./mainWindow";
 import { registerMediaPermissionsHandler } from "./mediaPermissions";
@@ -129,7 +133,7 @@ function init() {
     });
 }
 
-if (!app.requestSingleInstanceLock({ IS_DEV })) {
+if (!app.requestSingleInstanceLock({ IS_DEV, args: CommandLine })) {
     if (IS_DEV) {
         console.log("Vesktop is already running. Quitting previous instance...");
         init();
@@ -158,3 +162,10 @@ app.on("open-url", (_, url) => {
 app.on("window-all-closed", () => {
     if (process.platform !== "darwin") app.quit();
 });
+
+app.on("second-instance", (_e, _argv, _cwd, data) => {
+    const { args } = data as { args: typeof CommandLine; IS_DEV: boolean };
+    const { "run-shortcut": shortcut } = args.values;
+
+    if (shortcut) sendRendererCommand(IpcCommands.HANDLE_KEY_BIND, shortcut);
+});
diff --git a/src/main/keyBinds.ts b/src/main/keyBinds.ts
index 77cd174..0624030 100644
--- a/src/main/keyBinds.ts
+++ b/src/main/keyBinds.ts
@@ -11,6 +11,8 @@ import { sendRendererCommand } from "./ipcCommands";
 import { Settings } from "./settings";
 
 function unregisterKeyBinds() {
+    if (!app.isReady()) return;
+
     globalShortcut.unregisterAll();
 }
 
diff --git a/src/renderer/globalShortcuts/keybindHandler.ts b/src/renderer/globalShortcuts/keybindHandler.ts
index c6cbe4b..a7ad191 100644
--- a/src/renderer/globalShortcuts/keybindHandler.ts
+++ b/src/renderer/globalShortcuts/keybindHandler.ts
@@ -5,29 +5,51 @@
  */
 
 import { Logger } from "@vencord/types/utils";
+import { findByPropsLazy } from "@vencord/types/webpack";
+import { FluxDispatcher, StreamerModeStore } from "@vencord/types/webpack/common";
 
 import { ShortcutAction } from "./ShortcutSettings";
 
 const logger = new Logger("VesktopKeyBindHandler");
 
+const { selectVoiceChannel } = findByPropsLazy("selectVoiceChannel");
+
 export function handleKeyBind(keyBind: ShortcutAction) {
     logger.debug(`Handling key bind action: ${keyBind}`);
 
     switch (keyBind) {
         case "toggleMute":
+            FluxDispatcher.dispatch({
+                type: "AUDIO_TOGGLE_SELF_MUTE",
+                context: "default",
+                syncRemote: true,
+                playSoundEffect: true
+            });
             break;
+
         case "toggleDeafen":
+            FluxDispatcher.dispatch({
+                type: "AUDIO_TOGGLE_SELF_DEAF",
+                context: "default",
+                syncRemote: true
+            });
             break;
+
         case "toggleStreamerMode":
+            FluxDispatcher.dispatch({
+                type: "STREAMER_MODE_UPDATE",
+                key: "enabled",
+                value: !StreamerModeStore.enabled
+            });
             break;
-        case "toggleCamera":
-            break;
-        case "toggleScreenShare":
-            break;
+
         case "disconnectFromVoiceChannel":
+            selectVoiceChannel(null);
             break;
+
         case "unassigned":
             break;
+
         default:
             logger.warn(`Unknown key bind action: ${keyBind}`);
     }